2nd Alpine Winter Conference on Medicinal and Synthetic Chemistry

 St. Anton, Austria    January 19-23, 2020

Keynote Speakers

Expanding the Druggable Genome through Cereblon-Mediated Protein Degradation (KL02)

Dr Lawrence G. HAMANN
Dr Lawrence G. HAMANN
CELGENE, Cambridge, United States

Necessity is the Mother of Invention: Natural Products and the Chemistry They Inspire (KL01)

Prof. Sarah E. REISMAN
Prof. Sarah E. REISMAN
CALIFORNIA INSTITUTE OF TECHNOLOGY, Pasadena, United States
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Controlling the Fate and Function of Proteins with Photopharmacology (KL03)

Prof. Dirk TRAUNER
Prof. Dirk TRAUNER
NEW YORK UNIVERSITY, New York, United States
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Accelerating Drug Discovery by Intelligence Augmentation

Synthesis in the Chemical Space Age (PL18)

Prof. Timothy CERNAK
Prof. Timothy CERNAK
UNIVERSITY OF MICHIGAN, Ann Arbor, United States
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Organic Synthesis on a Computer: Should Medicinal Chemists Care? (PL17)

Prof. Bartosz A. GRZYBOWSKI
Prof. Bartosz A. GRZYBOWSKI
ULSAN NATIONAL INSTITUTE OF SCIENCE & TECHNOLOGY, Ulsan, Korea, South
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Accelerating R&D with Augmented Intelligence (PL19)

Dr Matthias ZENTGRAF
Dr Matthias ZENTGRAF
BOEHRINGER INGELHEIM, Biberach an der Riss, Germany
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Frontiers of Synthetic Chemistry

A Radical Way to Abeo-Steroids (PL08)

Prof. Philipp HERETSCH
Prof. Philipp HERETSCH
FREE UNIVERSITY OF BERLIN, Berlin, Germany
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New Avenues in Synthesis Enabled by Organic Photoredox Catalysis (PL06)

Prof. David NICEWICZ
Prof. David NICEWICZ
UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL, Chapel Hill, United States
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Late-Stage Functionalizations (PL07)

Prof. Tobias RITTER
Prof. Tobias RITTER
MAX-PLANCK-INSTITUT FÜR KOHLENFORSCHUNG, Mulheim, Germany
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Break-it-to-Make-it Strategies for Complex Molecule Synthesis (PL05)

Prof. Richmond SARPONG
Prof. Richmond SARPONG
UNIVERSITY OF CALIFORNIA, BERKELEY, Berkeley, United States
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Innovation and Inspiration from Natural Products

Discoveries and Surprises with Natural Products (PL14)

Prof. Karl GADEMANN
Prof. Karl GADEMANN
UNIVERSITY OF ZÜRICH, Zürich, Switzerland
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Concise Synthesis of Complex Taxane Diterpene Canataxpropellane by Photochemical Dearomatization (PL15)

Prof. Tanja GAICH
Prof. Tanja GAICH
UNIVERSITY OF KONSTANZ, Konstanz, Germany

Strategies for the Synthesis of Bioactive Diterpenoids (PL16)

Prof. Christopher VANDERWAL
Prof. Christopher VANDERWAL
UNIVERSITY OF CALIFORNIA, IRVINE, Irvine, United States
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Total Synthesis of Chivosazole F (OC04)

Dr Simon WILLIAMS
Dr Simon WILLIAMS
SYNGENTA, Stein AG, Switzerland
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Predictive ADME Sciences: Striking a Balance Between In Silico and Experimental Work?

Structural Attributes Influencing Unbound Tissue Distribution (PL01)

Dr Li DI
Dr Li DI
PFIZER, Groton, United States
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Metabolism of Strained Rings: Tales of the Unexpected (PL02)

Dr Martin HAYES
Dr Martin HAYES
ASTRAZENECA, Gothenburg, Sweden
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Title to be confirmed (PL04)

Dr Simone SCHADT
F. HOFFMANN-LA ROCHE, Basel, Switzerland
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Leveraging In Silico ADMET and Ancillary Pharmacology to Influence Selection of Chemical Series with Increase Probability of Success (PL03)

Dr Falgun SHAH
Dr Falgun SHAH
MERCK, West Point, United States
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Dr Kenichi UMEHARA
Dr Kenichi UMEHARA
ROCHE PHARMACEUTICAL RESEARCH AND EARLY DEVELOPMENT, Basel, Switzerland
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Protein Degradation: New Rules for Drug Discovery

Expanding the Druggable Genome through Cereblon-Mediated Protein Degradation (KL02)

Dr Lawrence G. HAMANN
Dr Lawrence G. HAMANN
CELGENE, Cambridge, United States
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Targeted Protein Degradation (PL12)

Prof. Andy PHILLIPS
Prof. Andy PHILLIPS
C4 THERAPEUTICS, Watertown, United States
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Four E3 Ligases, One Target: Towards Novel CDK6 Protacs (OC03)

Mr Christian STEINEBACH
Mr Christian STEINEBACH
UNIVERSITY OF BONN, Bonn, Germany
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Structure and Biophysics - Companions for Medicinal Chemistry

Title to be confirmed (PL11)

Dr Xavier DARZACQ
Dr Xavier DARZACQ
UNIVERSITY OF CALIFORNIA, BERKELEY, Berkeley, United States

Membrane Proteins at the SGC – Challenges and Success Stories (PL09)

Dr Katharina DUERR
Dr Katharina DUERR
UNIVERSITY OF OXFORD, Oxford, United Kingdom
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Discovery of Small Molecule Fascin 1 Inhibitors Using Fragment-Based Drug Discovery (OC02)

Dr Stuart FRANCIS
Dr Stuart FRANCIS
THE BEATSON INSTITUTE FOR CANCER RESEARCH, Glasgow, United Kingdom
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Title to be confirmed (PL10)

Dr Matthias FRECH
Dr Matthias FRECH
MERCK, Darmstadt, Germany

Targeted Delivery - Strategies to Help your Drug Substances get to the Right Place

Using Small Molecules to Engineer and Explore Human Immunity (PL22)

Prof. David SPIEGEL
Prof. David SPIEGEL
YALE UNIVERSITY, New Haven, United States
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Intracellular and Tissue Specific Targeting of Therapeutic Modalities (PL21)

Dr Vadim DUDKIN
Dr Vadim DUDKIN
JANSSEN DISCOVERY SCIENCES, Lansdale, United States
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Title to be confirmed (PL23)

Dr Valerie ODEGARD
Dr Valerie ODEGARD
SILVERBACK THERAPEUTICS, Seattle, United States
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Discovery of Tumor Targeted TLR7/8 Immune-Stimulating Antibody Conjugates (ISAC) (PL20)

Dr Brian SAFINA
Dr Brian SAFINA
BOLT BIOTHERAPEUTICS, Redwood City, United States
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